We are targeting diseases with significant unmet needs including Duchenne Muscular Dystrophy, Epidermolysis Bullosa, and Ischemic Stroke.
XITRA
Activation of the Alternative RAS through the Mas and MrgD receptors leads to a variety of biologic effects and the potential to develop drug therapies for a wide range of diseases.
SCIENCE
The alternative renin angiotensin system (RAS) is a counter regulatory pathway to the classical RAS. The “classical” renin angiotensin system (RAS) comprises Angiotensin Converting Enzyme (ACE), its peptide product Angiotensin II, and the peptide’s receptor, AT1. This system, which controls blood pressure, and fluid and electrolyte balance, was discovered in the first half of the 20th century.
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